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Refined enzymatic extraction technology

With batch scalable and stable extraction technology formed by refined enzyme extraction process parameter, the extracted collagen keep its natural conformation and biology activity. Meanwhile, self-developed quantitative analysis is utilized to authenticate indicators including active collagen molecular weight and triple-helix structure and so on to ensure the stability of product quality.

Preparation of high purity collagen

The collagen features by high purity, qualified as advance level in globe. Adopt self-designed collagen refined-preparation equipment and high through-put purified process for the sake of high purifying, which, significantly shortens the purifying cycle with better stability in batches, comparing to traditional purifying technology.

Immunogenicity elimination from animal-originated material

The refined process parameter selectively cut and remove telopeptide and effectively clear the potential immunogenicity components, after which, the collagen has good bio-compatibility and minimum risk of immunogenicity and allergic reaction.

Raw material pre-processing technology with high precision

By adopting pre-processing technology with self-developed process,formulation and process parameter, the microbial and impurities in the raw material can be effectively cleared, which, helps to control kreotoxin level in bacteria and the material is homogenized and crushed without damaging the collagen activity.

Efficient virus inactivation technology

The unique pathogenic microorganism control and inactivation process effectively prevent the likelihood of pathogenic microorganisms carried by animal tissues which pose a safety risk for products, and effectively inactivates the virus without destroying the activity and natural structure of collagen.

Final sterilization technology for products

With sterilization of collagen solution or liquid collagen products by combining various special conditions, the product can achieve sterility (SAL=10-6) while avoiding denaturation and deactivation of collagen during sterilization, which effectively maintains the natural conformation and biological activity of collagen. It is the first final sterilization technology in China that is applicable to liquid collagen products while the biological activity of collagen is maintained.

生物(wù)医用(yòng)级活性胶原大规模无菌提取制备技术